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Gene Expression Data
Assay Details
Assay
Reference: J:331972 Hummel D, et al., Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons. Development. 2022 Nov 15;149(22):dev200553
Assay type: RNA in situ
MGI Accession ID: MGI:7495504
Gene symbol: Wnt5a
Gene name: wingless-type MMTV integration site family, member 5A
Probe: Wnt5a probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present Regionally restricted 1B Expression (white arrows) was absent in rhombomere 4 (r4), extended medially up to the r3/r4 boundary.
TS19: hindbrain ventricular layer Present Regionally restricted 1B Expressed in a broad domain in the caudal hindbrain from the r4/r5 boundary.
Specimen S1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain floor plate Weak Regionally restricted S1B Expressed in rostral midline tissues.
Specimen S1B r2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 floor plate Weak S1B r2
Specimen S1B r3: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 3 floor plate Absent S1B r3 Expressed only in rostral midline tissues.
Specimen S1B r4: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 floor plate Absent S1B r4 Expressed only in rostral midline tissues.
Specimen S1B r5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 floor plate Absent S1B r5 Expressed only in rostral midline tissues.
Specimen S1D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present Regionally restricted S1D Expressed at a higher level up to the r3/r4 boundary.
TS19: hindbrain ventricular layer Strong Regionally restricted S1D Expressed strongly in the ventricular zone in r5 and more posterior rhombomeres.
Specimen S1D r2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present S1D r2
Specimen S1D r3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present S1D r3
Specimen S1D r4: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present Regionally restricted S1D r4 No expression in midline tissues in rhombomere 4 (r4).
Specimen S1D r5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present Regionally restricted S1D r5 No expression in midline tissues in rhombomere 5 (r5).
TS19: hindbrain ventricular layer Strong S1D r5
Specimen S6C: embryonic day 12.5; Egr2tm2(cre)Pch/Egr2+, Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindbrain lateral wall Strong Patchy S6C Ectopic and robust expression throughout rhombomere 3 (r3), and in a broad domain in the caudal hindbrain from the r4/r5 boundary.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory