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Gene Expression Data
Assay Details
Assay
Reference: J:280803 Ma J, et al., Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. PLoS Biol. 2019 Oct;17(10):e3000461
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7494030
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: anti-CTIP2 [25B6] (ab18465)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S2A: postnatal day 56; Dip2aem#bYwz/Dip2a+ (more )
Note: Double labeled: red - Bcl11b; green - Dip2a reporter (assay MGI:7494027).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex cerebral cortex pyramidal neuron Present Regionally restricted S2A Merge (right) , S2A CTIP2 Expression in pyramidal neurons in internal layers.

Specimen S3J CTIP2 WT: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present S3J CTIP2 WT

Specimen S3J CTIP2 KO: postnatal day 56; Dip2aem#aYwz/Dip2aem#aYwz (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present S3J CTIP2 KO No apparent difference in cortical lamination compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory