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Gene Expression Data
Assay Details
Assay
Reference: J:280803 Ma J, et al., Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. PLoS Biol. 2019 Oct;17(10):e3000461
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7494029
Gene symbol: Cux1
Gene name: cut-like homeobox 1
Antibody: anti-CUTL1/CUX1/CDP (SS9) (sc-101003)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S2A: postnatal day 56; Dip2aem#bYwz/Dip2a+ (more )
Note: Double labeled: red - Cux1; green - Dip2a reporter (assay MGI:7494027).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex cerebral cortex pyramidal neuron Present Regionally restricted S2A CUX1 , S2A Merge (left) Expression in pyramidal neurons in external layers.
Specimen S3J CUX1 WT: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present S3J CUX1 WT
TS28: cortical layer III Present S3J CUX1 WT
TS28: cortical layer IV Present S3J CUX1 WT
Specimen S3J CUX1 KO: postnatal day 56; Dip2aem#aYwz/Dip2aem#aYwz (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present S3J CUX1 KO No apparent difference in cortical lamination compared to wild type.
TS28: cortical layer III Present S3J CUX1 KO No apparent difference in cortical lamination compared to wild type.
TS28: cortical layer IV Present S3J CUX1 KO No apparent difference in cortical lamination compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory