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Gene Expression Data
Assay Details
Assay
Reference: J:177585 Hesse K, et al., AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7492153
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-Caspase-3
Detection system: Secondary antibody
Results
Specimen 3a Caspase-3 E13 +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Absent 3a E13 Caspase-3 +/+
Specimen 3a Caspase-3 E13 -/-: embryonic day 13.5; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS21: brain Absent 3a E13 Caspase-3 -/-
Specimen 3a Caspase-3 E15 +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Absent 3a E15 Caspase-3 +/+
Specimen 3a Caspase-3 E15 -/-: embryonic day 15.5; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS23: midbrain Present Single cells 3a E15 Caspase-3 -/- Expression in single cells in posterior midbrain at E15.
Specimen 3a Caspase-3 E17 +/+: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Absent 3a E17 Caspase-3 +/+
Specimen 3a Caspase-3 E17 -/-: embryonic day 17.5; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS25: midbrain Strong Regionally restricted 3a E17 Caspase-3 -/- Dramatic increase in number of expressing cells in posterior midbrain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory