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Gene Expression Data
Assay Details
Assay
Reference: J:276308 Koyano-Nakagawa N, et al., Feedback Mechanisms Regulate Ets Variant 2 (Etv2) Gene Expression and Hematoendothelial Lineages. J Biol Chem. 2015 Nov 20;290(47):28107-19
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7488101
Gene symbol: Flt1
Gene name: FMS-like tyrosine kinase 1
Reporter: lacZ
Direct Detection
Results
Specimen 7Ca: embryonic day 8.75; Flt1tm1Jrt/Flt1+ (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Ca Normal vascular patterning was observed.
Specimen 7Cb: embryonic day 8.75; Flt1tm1Jrt/Flt1tm1Jrt (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Cb Excessive Flt1-LacZ-positive cells were detected. Significant vascular phenotypes were observed in the Flt1-KO.
Specimen 7Cc: embryonic day 8.75; Etv2tm1.1Djg/Etv2tm1.1Djg, Flt1tm1Jrt/Flt1tm1Jrt, Kdrtm1(cre)Sato/Kdr+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: vascular system Present 7Cc The Flt1 KO; Etv2 CKO embryos had an intermediate phenotype.
Specimen 7Cd: embryonic day 8.75; Flt1tm1Jrt/Flt1+ (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Cd Normal vascular patterning was observed.
Specimen 7Ce: embryonic day 8.75; Flt1tm1Jrt/Flt1tm1Jrt (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Ce Excessive Flt1-LacZ-positive cells were detected. Significant vascular phenotypes were observed in the Flt1-KO.
Specimen 7Cf: embryonic day 8.75; Etv2tm1.1Djg/Etv2tm1.1Djg, Flt1tm1Jrt/Flt1tm1Jrt, Kdrtm1(cre)Sato/Kdr+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: vascular system Present 7Cf The Flt1 KO; Etv2 CKO embryos had an intermediate phenotype.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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