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Gene Expression Data
Assay Details
Assay
Reference: J:331874 Lee H, et al., Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7488008
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Antibody: anti-type X collagen (ab49945)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen Ia: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cartilage Present Regionally restricted 1Ia Expression is in a single segment of hypertrophic cartilage.
TS23: femur Present Regionally restricted 1Ia Expression is in a single segment of hypertrophic cartilage.
Specimen Ig: embryonic day 15.5; Atad3atm1a(KOMP)Wtsi/Atad3atm1a(KOMP)Wtsi, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cartilage Present Regionally restricted 1Ig Expression in this mutant is comparable to controls.
TS23: femur Present Regionally restricted 1Ig Expression in this mutant is comparable to controls.
Specimen Ic: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cartilage Present Regionally restricted 1Ic Expression is in hypertrophic cartilage in two segments toward both ends.
TS24: femur Present Regionally restricted 1Ic Expression is in hypertrophic cartilage in two segments toward both ends.
Specimen Ii: embryonic day 16.5; Atad3atm1a(KOMP)Wtsi/Atad3atm1a(KOMP)Wtsi, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: cartilage Present Regionally restricted 1Ii In this mutant expression is in a single segment of hypertrophic cartilage.
TS24: femur Present Regionally restricted 1Ii In this mutant expression is in a single segment of hypertrophic cartilage.
Specimen 2Cb: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cartilage Present 2Cb
TS27: femur Present 2Cb
Specimen 2Cf: postnatal day 0; Atad3atm1a(KOMP)Wtsi/Atad3atm1a(KOMP)Wtsi, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cartilage Present 2Cf Expression in this mutant is the same as in controls.
TS27: femur Present 2Cf Expression in this mutant is the same as in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory