Nefh Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:299026 Kannan-Sundhari A, et al., Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival. Front Cell Dev Biol. 2020;8:576654
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7470863
Gene symbol:	Nefh
Gene name:	neurofilament, heavy polypeptide

Antibody:

Results

3A +/+ ©

Specimen 3A Brd4+/+: postnatal day 16 (more

)

Structure	Level	Pattern	Image	Note
TS28: cochlea	Present	Regionally restricted	3A +/+	Expression is in fiber bundles.

3A -/- P16 ©

Specimen 3A Atoh1-Brd4^-/- P16: postnatal day 16; Brd4^{tm1c(EUCOMM)Wtsi}/Brd4^{tm1c(EUCOMM)Wtsi}, Tg(Atoh1-cre)1Bfri/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: cochlea	Present	Non-Uniform	3A -/- P16	Staining in this mutant indicates improper fasciculation.

3A -/- P21 ©

Specimen 3A Atoh1-Brd4^-/- P21: postnatal day 21; Brd4^{tm1c(EUCOMM)Wtsi}/Brd4^{tm1c(EUCOMM)Wtsi}, Tg(Atoh1-cre)1Bfri/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: cochlea	Present	Non-Uniform	3A -/- P21	Staining indicated fiber bundle degeneration.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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