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Gene Expression Data
Assay Details
Assay
Reference: J:332245 Liaci C, et al., Loss of ARHGAP15 affects the directional control of migrating interneurons in the embryonic cortex and increases susceptibility to epilepsy. Front Cell Dev Biol. 2022;10:875468
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7470705
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Reporter: GFP
Direct Detection
Results
Specimen 1A E11.5: embryonic day 11.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS19: telencephalon Present 1A E11.5 fourth , 1A E11.5 first , 1A E11.5 second , 1A E11.5 third
Specimen 1A E12.5: embryonic day 12.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS20: telencephalon Present 1A E12.5 third , 1A E12.5 fourth , 1A E12.5 second , 1A E12.5 first
Specimen 1B left: embryonic day 14.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS22: telencephalon Present 1B''' left , 1B' left , 1B'' left
Specimen 1B middle: embryonic day 14.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS22: telencephalon Present 1B' middle , 1B'' middle , 1B''' middle
Specimen 1B right: embryonic day 14.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS22: telencephalon Present 1B''' right , 1B' right , 1B'' right
Specimen 1C left: postnatal day 2; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS27: cerebral cortex Present 1C' left , 1C''' left , 1C'' left
Specimen 1C right: postnatal day 45; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: green - Gad1 reporter; red - Arhgap15 reporter (assay MGI:7470704).
Structure Level Pattern Image Note
TS28: cerebral cortex Present 1C ''' right , 1C' right , 1C'' right
Specimen 1D E14.5: embryonic day 14.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present 1D E14.5
Specimen 1D P45: postnatal day 45; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 1D P45
Specimen 4A left: embryonic day 14.5; Gad1tm1.1Tama/Gad1+ (more )
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex cortical interneuron Present Regionally restricted 4A left Expression is in tangentially migrating cortical interneurons.
Specimen 4A right: embryonic day 14.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex cortical interneuron Present Regionally restricted 4A right Expression in tangentially migrating cortical interneurons is the same as controls.
Specimen 5A left: embryonic day 17.5; Gad1tm1.1Tama/Gad1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: cerebral cortex cortical interneuron Present Regionally restricted 5A left bottom , 5A left top Expression is in tangentially migrating cortical interneurons.
Specimen 5A right: embryonic day 17.5; Arhgap15tm1Ehi/Arhgap15+, Gad1tm1.1Tama/Gad1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: cerebral cortex cortical interneuron Present Regionally restricted 5A right bottom , 5A right top Expression is in radially migrating cortical interneurons that may have altered trajectories with respect to the canonical radial direction.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory