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Gene Expression Data
Assay Details
Assay
Reference: J:221769 Bridges JP, et al., Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. Am J Respir Cell Mol Biol. 2013 Sep;49(3):348-57
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7469455
Gene symbol: Adgrf5
Gene name: adhesion G protein-coupled receptor F5
Antibody: anti-GPR116
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1D: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: lobar bronchus epithelium multiciliated epithelial cell of the bronchus Present 1D Expressed in cilia on proximal airway cells. Not expressed on other epithelial cells.
TS28: lobar bronchus epithelium club cell Absent 1D
TS28: lobar bronchus epithelium neuroendocrine cell of epithelium of lobar bronchus Absent 1D
Specimen 1D inset: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 1D inset Expressed on the apical surface.
TS28: alveolus epithelium pulmonary alveolar type 2 cell Present 1D inset Expressed on the apical surface.
Specimen E3C WT: postnatal adult (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present E3C WT
Specimen E3C mut: postnatal adult; Adgrf5tm1.2Jpbs/Adgrf5tm1.2Jpbs (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present E3C MUT Decreased staining and loss of plasma membrane localization were seen, in a discontinuous staining pattern.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory