Mip Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:226036 Maddala R, et al., Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7464778
Gene symbol:	Mip
Gene name:	major intrinsic protein of lens fiber

Antibody:	Anti-aquaporin-0
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

10_upper WT ©

Specimen 10 WT: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lens epithelium	Absent		10_upper WT
TS25: lens fiber	Present		10_upper WT

10_upper cKO ©

Specimen 10 cKO: embryonic day 17.5; Rap1a^tm1Morz/Rap1a^tm1Morz, Rap1b^tm1Morz/Rap1b^tm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lens fiber	Present		10_upper cKO	Similar as in the wild-type.
TS25: lens epithelium	Present	Regionally restricted	10_upper cKO	In some specimens, expressed in the apical surface of lens epithelium.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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