About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:334174 Wang Y, et al., Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight. J Clin Invest. 2021 May 3;131(9)
Assay type: Recombinase reporter
MGI Accession ID: MGI:7447194
Gene symbol: Mc4r
Gene name: melanocortin 4 receptor
Reporter: tdTomato
Direct Detection
Results
Specimen Sup1C BST: postnatal; Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/Gt(ROSA)26Sor+, Mc4rem2(cre)Vai/Mc4rem2(cre)Vai (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: bed nucleus of stria terminalis cerebral cortex neuron Present S1C top left
Specimen Sup1C PVN: postnatal; Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/Gt(ROSA)26Sor+, Mc4rem2(cre)Vai/Mc4rem2(cre)Vai (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus cerebral cortex neuron Present S1C top center
Specimen Sup1C CeM: postnatal; Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/Gt(ROSA)26Sor+, Mc4rem2(cre)Vai/Mc4rem2(cre)Vai (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: central amygdaloid nucleus cerebral cortex neuron Present S1C top right
Specimen Sup1C DMH: postnatal; Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/Gt(ROSA)26Sor+, Mc4rem2(cre)Vai/Mc4rem2(cre)Vai (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dorsomedial hypothalamic nucleus cerebral cortex neuron Present S1C bottom left
TS28: lateral hypothalamic area cerebral cortex neuron Present S1C bottom left
TS28: ventromedial hypothalamic nucleus cerebral cortex neuron Present S1C bottom left
Specimen Sup1C LPBN: postnatal; Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/Gt(ROSA)26Sor+, Mc4rem2(cre)Vai/Mc4rem2(cre)Vai (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: parabrachial nucleus cerebral cortex neuron Present S1C bottom center
Specimen Sup1C NTS: postnatal; Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/Gt(ROSA)26Sor+, Mc4rem2(cre)Vai/Mc4rem2(cre)Vai (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dorsal motor nucleus of vagus nerve cerebral cortex neuron Strong S1C bottom right
TS28: solitary tract nucleus cerebral cortex neuron Strong S1C bottom right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory