Lrig1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:202041 Page ME, et al., The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell. 2013 Oct 3;13(4):471-82
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:7442826
Gene symbol:	Lrig1
Gene name:	leucine-rich repeats and immunoglobulin-like domains 1

Reporter:	GFP
Antibody:	anti-GFP (ab13970)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

1C ©

1D ©

Specimen 1C/D: postnatal adult; Lrig1^{tm1(cre/ERT2)Kjen}/Lrig1⁺ (more

)
Note: Back skin in telogen (resting) phase. Double labeled: green - Lrig1 reporter; red - Lrig protein (assay MGI:7443158).

Structure	Level	Pattern	Image	Note
TS28: hair follicle	Present	Regionally restricted	1C , 1D	Expression is seen in the junctional zone.
TS28: sebaceous gland	Present		1C , 1D

1J ©

Specimen 1J: postnatal adult; Lrig1^{tm1(cre/ERT2)Kjen}/Lrig1⁺ (more

)
Note: Back skin in telogen (resting) phase. Double labeled: green - Lrig1; red - Prdm1 (assay MGI:7443212).

Structure	Level	Pattern	Image	Note
TS28: sebaceous gland	Present	Regionally restricted	1J	Expression is seen in the basal layer, not in suprabasal cells.

S2B ©

S2C ©

Specimen S2B/C: postnatal adult; Lrig1^{tm1(cre/ERT2)Kjen}/Lrig1⁺ (more

)
Note: Tail epidermis. Double labeled: green - Lrig1 reporter; red - Lrig protein (assay MGI:7443158).

Structure	Level	Pattern	Image	Note
TS28: sebaceous gland	Present		S2B , S2C

S2D ©

Specimen S2D: postnatal adult; Lrig1^{tm1(cre/ERT2)Kjen}/Lrig1⁺ (more

)
Note: Tail epidermis. Double labeled: green - Lrig1; red - Cd34 (assay MGI:7443208).

Structure	Level	Pattern	Image	Note
TS28: sebaceous gland	Present		S2D

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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