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Gene Expression Data
Assay Details
Assay
Reference: J:263835 Newman EA, et al., Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Dev Biol. 2018 Jul 15;439(2):102-111
Assay type: RNA in situ
MGI Accession ID: MGI:7442820
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe
Probe preparation: Antisense RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2N: embryonic day 12.5; Foxd1tm1(GFP/cre)Amc/Foxd1+ (more )
Structure Level Pattern Image Note
TS20: prethalamus Present 2N
TS20: hypothalamus mantle layer Present Regionally restricted 2N Expressed in the ventral anterior hypothalamus.
TS20: hypothalamus ventricular layer Present Regionally restricted 2N Expressed in the ventral anterior hypothalamus.

Specimen 2O: embryonic day 12.5; Foxd1tm1(GFP/cre)Amc/Foxd1tm1(GFP/cre)Amc (more )
Structure Level Pattern Image Note
TS20: prethalamus Present 2O Reduced expression compared with the control.
TS20: hypothalamus ventricular layer Weak Regionally restricted 2O More dramatic reduction in the ventricular zone than in the mantle zone of the ventral anterior hypothalamus, compared with the control.
TS20: hypothalamus mantle layer Present Regionally restricted 2O Reduced expression in the ventral anterior hypothalamus compared with the control.

Specimen 5M: postnatal day 0; Foxd1tm1(GFP/cre)Amc/Foxd1+ (more )
Structure Level Pattern Image Note
TS27: reticular thalamic nucleus Present 5M
TS27: suprachiasmatic nucleus Present 5M

Specimen 5N: postnatal day 0; Foxd1tm1(GFP/cre)Amc/Foxd1tm1(GFP/cre)Amc (more )
Structure Level Pattern Image Note
TS27: suprachiasmatic nucleus Weak 5N Dramatically reduced expression compared with the control.
TS27: reticular thalamic nucleus Present 5N Similar as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory