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Gene Expression Data
Assay Details
Assay
Reference: J:333149 Zhao T, et al., Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators. Biol Reprod. 2022 Jul 25;107(1):135-147
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437576
Gene symbol: Cdkn1b
Gene name: cyclin dependent kinase inhibitor 1B
Antibody: anti-p27 KIP1 [EPFHCR16] (ab92741)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixation was with Hartman's fixative.
Results
Specimen S2 CDKN1B P14 Control: postnatal day 14; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present S2_CDKN1B P14 Control
Specimen S2 CDKN1B P14 AcP1KO: postnatal day 14; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Strong S2_CDKN1B P14 AcP1KO Increase in Sertoli cell expression compared to control.
Specimen S2 CDKN1B Adult Control: postnatal adult; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present S2_CDKN1B Adult Control
Specimen S2 CDKN1B Adult AcP1KO: postnatal adult; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Strong S2_CDKN1B Adult AcP1KO Increase in Sertoli cell expression compared to control.
Specimen 5E CDKN1B Control: postnatal day 14; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 5E CDKN1B Control
Specimen 5E CDKN1B AcP1KO: postnatal day 14; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Strong 5E CDKN1B AcP1KO Increase in Sertoli cell expression compared to control.
Specimen 5E CDKN1B AcP1KO; Cdkn1b+/-: postnatal day 14; Cdkn1btm1Mlf/Cdkn1b+, Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Weak 5E CDKN1B AcP1KO; Cdkn1b+/- Expression in Sertoli cells reduced compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory