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Gene Expression Data
Assay Details
Assay
Reference: J:333071 Ma H, et al., MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors. EMBO Rep. 2021 Jul 5;22(7):e52150
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7434963
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-Eomes/Tbr2 (ab23345)
Detection system: Secondary antibody
Results
Specimen 3A WT: embryonic day 16.5 (more )
Note: Double labeled: green - Tbr2 (Eomes); red - Brdu.
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 3A WT Tbr2 , 3A WT Merge
TS24: cerebral cortex ventricular layer Present 3A WT Tbr2 , 3A WT Merge
Specimen 3A KO: embryonic day 16.5; Macroh2a1em1Jwji/Macroh2a1em1Jwji (more )
Note: Double labeled: green - Tbr2 (Eomes); red - Brdu.
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 3A KO Tbr2 , 3A KO Merge Authors state that the number of expressing cells increased more significantly than in wild type.
TS24: cerebral cortex ventricular layer Present 3A KO Tbr2 , 3A KO Merge Authors state that the number of expressing cells increased more significantly than in wild type.
Specimen S2A TBR2 WT: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present S2A TBR2 WT
Specimen S2A TBR2 KO: embryonic day 13.0; Macroh2a1em1Jwji/Macroh2a1em1Jwji (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present S2A TBR2 KO Not significantly altered compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory