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Gene Expression Data
Assay Details
Assay
Reference: J:283394 Hughes LJ, et al., Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7434460
Gene symbol: Pcna
Gene name: proliferating cell nuclear antigen
Antibody: anti-PCNA (10205-2-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3M WT: embryonic day 16.5 (more )
Note: Double labeled: green - Pcna; red - pH3.
Structure Level Pattern Image Note
TS24: cerebellum external granule cell layer Present 3M WT

Specimen 3M dCKO: embryonic day 16.5; Tg(Nes-cre)1Atp/0, Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: green - Pcna; red - pH3.
Structure Level Pattern Image Note
TS24: cerebellum external granule cell layer Present 3M CKO The proportion of pH3+ cells among Pcna+ cells was unchanged despite the significantly reduced number of pH3+ cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory