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Gene Expression Data
Assay Details
Assay
Reference: J:146765 Golonzhka O, et al., Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7433204
Gene symbol: Amelx
Gene name: amelogenin, X-linked
Results
Specimen 1H/J: embryonic day 18.5 (more )
Note: Double labeled: red - Amelx; green - Bcl11b (assay MGI:7433203).
Structure Cell Type Level Pattern Image Note
TS26: stratum intermedium Present 1J , 1H
TS26: inner enamel epithelium ameloblast Strong 1H , 1J Expressed in the nuclei.

Specimen 3A: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Present Regionally restricted 3A Ameloblasts developed only on the labial side, while epithelial cells populated the lingual aspect.

Specimen 3B: embryonic day 18.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Weak 3B Severely reduced expression compared with the wild-type. Ameloblasts were reduced in size.

Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present 3C Ameloblasts developed only on the labial side, while epithelial cells populated the lingual aspect.

Specimen 3D: embryonic day 18.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Present 3D A secondary ameloblast-like layer was present on the lingual side in the mutant.

Specimen 3E: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Present 3E
TS26: stratum intermedium Present 3E

Specimen 3F: embryonic day 18.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Weak 3F Ameloblasts were with deformed or absent adhesion points on the labial side.
TS26: stratum intermedium Present 3F

Specimen 3U: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: inner enamel epithelium ameloblast Present 3U

Specimen 3V: embryonic day 16.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS24: inner enamel epithelium ameloblast Weak 3V Strongly down-regulated expression compared with the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory