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Gene Expression Data
Assay Details
Assay
Reference: J:75868 Lu QR, et al., Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
Assay type: RNA in situ
MGI Accession ID: MGI:7432579
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 probe
Probe preparation: Antisense RNA
Results
Specimen 2A +/+ E12.5: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: spinal cord ventricular layer spinal cord oligodendrocyte Present Regionally restricted 2A Sox10 E12.5 +/+ Expressed in early oligodendrocytes in the ventral ventricular zone of the neural tube at the forelimb level.
Specimen 2A -/- E12.5: embryonic day 12.5; Olig2tm1Rth/Olig2tm1Rth (more )
Structure Level Pattern Image Note
TS20: spinal cord Absent 2A Sox10 E12.5 -/-
Specimen 2A +/+ E14.5: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: spinal cord spinal cord oligodendrocyte Present 2A Sox10 E14.5 +/+
Specimen 2A -/- E14.5: embryonic day 14.5; Olig2tm1Rth/Olig2tm1Rth (more )
Structure Level Pattern Image Note
TS22: spinal cord Absent 2A Sox10 E14.5 -/-
Specimen 2A +/+ E18.5: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 2A Sox10 E18.5 +/+
Specimen 2A -/- E18.5: embryonic day 18.5; Olig2tm1Rth/Olig2tm1Rth (more )
Structure Level Pattern Image Note
TS26: spinal cord Absent 2A Sox10 E18.5 -/-
Specimen 2C Olig1+/-: postnatal day 0; Olig1tm1(cre)Rth/Olig1+ (more )
Structure Level Pattern Image Note
TS27: spinal cord white matter Present 2C Sox10 +/- Expressed in oligodendrocyte progenitor cells.
Specimen 2C Olig1-/-: postnatal day 0; Olig1tm1(cre)Rth/Olig1tm1(cre)Rth (more )
Structure Level Pattern Image Note
TS27: spinal cord white matter Present 2C Sox10 -/- Expression was clearly delayed compared with the control.
Specimen 3A dorsal +/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: forebrain oligodendrocyte precursor cell Present 3A-5
Specimen 3A dorsal -/-: embryonic day 18.5; Olig2tm1Rth/Olig2tm1Rth (more )
Structure Cell Type Level Pattern Image Note
TS26: forebrain oligodendrocyte precursor cell Present Regionally restricted 3A-6 There was no expression in the dorsal region. Only a small collection of positive cells in the ventral region.
Specimen 3A ventral +/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: forebrain oligodendrocyte precursor cell Present 3A-7
Specimen 3A ventral -/-: embryonic day 18.5; Olig2tm1Rth/Olig2tm1Rth (more )
Structure Cell Type Level Pattern Image Note
TS26: forebrain oligodendrocyte precursor cell Present Regionally restricted 3A-8 Only a small collection of positive cells in the ventral region.
Specimen 3B +/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: hindbrain oligodendrocyte precursor cell Present 3B-7 , 3B-5
Specimen 3B -/-: embryonic day 18.5; Olig2tm1Rth/Olig2tm1Rth (more )
Structure Cell Type Level Pattern Image Note
TS26: hindbrain oligodendrocyte precursor cell Present 3B-8 , 3B-6 Nearly normal numbers of positive cells compared with the wild-type.
Specimen 7A: embryonic day 12.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant. Double labeled: purple - Sox10; blue - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS20: spinal cord lateral wall spinal cord oligodendrocyte Present 7A 12.5 LacZ/Sox10 Expressed in early oligodendrocytes. Colocalization with Olig1-Cre linage expression was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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