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Gene Expression Data
Assay Details
Assay
Reference: J:220452 Nasif S, et al., Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):E1861-70
Assay type: RT-PCR
MGI Accession ID: MGI:7432578
Gene symbol: Pomc
Gene name: pro-opiomelanocortin-alpha
Results
Image: 6A ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Isl1loxP/loxP P TS28: hypothalamus Present Not Specified involves: 129S6/SvEvTac Isl1tm2Gan/Isl1tm2GanMale
PomcIsl1/KO P TS28: hypothalamus Present (a) Not Specified involves: 129S6/SvEvTac * FVB/N Isl1tm2Gan/Isl1tm2Gan, Tg(Pomc1-cre)1Gsb/0Male Conditional mutant.
Isl1loxP/loxP P TS28: hypothalamus Present Not Specified involves: 129S6/SvEvTac Isl1tm2Gan/Isl1tm2GanFemale
PomcIsl1/KO P TS28: hypothalamus Present (a) Not Specified involves: 129S6/SvEvTac * FVB/N Isl1tm2Gan/Isl1tm2Gan, Tg(Pomc1-cre)1Gsb/0Female Conditional mutant.
Notes:
(a) Expression levels are 25% of that of control mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory