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Gene Expression Data
Assay Details
Assay
Reference: J:198469 Yang Y, et al., Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation. Dev Biol. 2013 Jun 15;378(2):94-106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7432355
Gene symbol: Mbp
Gene name: myelin basic protein
Antibody: anti-MBP
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1G/I: embryonic day 18.0 (more )
Note: Double labeled: green -Mbp; red - BrdU.
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 1I , 1G Distributed more widely throughout the dorso-ventral axis with a higher concentration in ventral regions.
Specimen 1J/L: embryonic day 18.0; Cdk5tm1Kul/Cdk5tm1Kul (more )
Note: Double labeled: green -Mbp; red - BrdU.
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present Regionally restricted 1L , 1J Reduced number of the positive cells compared with the wild-type (quantified in 1M). Primarily localized to ventral midline regions. No significant differences in proliferation.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory