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Gene Expression Data
Assay Details
Assay
Reference: J:332642 Cohen-Gulkar M, et al., The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431188
Gene symbol: Cdh3
Gene name: cadherin 3
Antibody: anti-P-cadherin (132000z)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C: embryonic day 12.5; Lhx2tm1Monu/Lhx2tm1Monu (more )
Note: Double labeled: green - Cdh3; red - Lhx2 (assay MGI:7431191).
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present 1C , 1C inset merge , 1C inset Cdh3 Expression in single epithelial layer.
Specimen 1D: embryonic day 12.5; Lhx2tm1Monu/Lhx2tm1Monu, Tg(Dct-cre)1Apdn/0 (more )
Note: Conditional mutant. Double labeled: green - Cdh3; red - Lhx2 (assay MGI:7431191).
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Absent 1D inset merge , 1D inset Cdh3 , 1D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory