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Gene Expression Data
Assay Details
Assay
Reference: J:332642 Cohen-Gulkar M, et al., The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431191
Gene symbol: Lhx2
Gene name: LIM homeobox protein 2
Antibody: anti-Lhx2 (C-20; sc-19344)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1C: embryonic day 12.5; Lhx2tm1Monu/Lhx2tm1Monu (more )
Note: Double labeled: red - Lhx2; green - Cdh3 (assay MGI:7431188).
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present 1C inset Lhx2 , 1C inset merge , 1C Expression in single epithelial layer.
Specimen 1D: embryonic day 12.5; Lhx2tm1Monu/Lhx2tm1Monu, Tg(Dct-cre)1Apdn/0 (more )
Note: Conditional mutant. Double labeled: red - Lhx2; green - Cdh3 (assay MGI:7431188).
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Absent 1D , 1D inset Lhx2 , 1D inset merge
Specimen 1K: embryonic day 16.5; Lhx2tm1Monu/Lhx2tm1Monu (more )
Note: Double labeled: red - Lhx2; green - Sox9 (assay MGI:7431197).
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Present 1K inset Lhx2 , 1K inset merge , 1K
Specimen 1L: embryonic day 16.5; Lhx2tm1Monu/Lhx2tm1Monu, Tg(Dct-cre)1Apdn/0 (more )
Note: Conditional mutant. Double labeled: red - Lhx2; green - Sox9 (assay MGI:7431197).
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Absent 1L , 1L inset Lhx2 , 1L inset merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory