Gene Expression Data
Assay Details
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Assay
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Reference:
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J:207523
Edlund RK, et al., Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers. Dev Biol. 2014 Jun 1;390(1):1-13
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7428448
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Gene symbol:
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Sox10
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Gene name:
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SRY (sex determining region Y)-box 10
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Probe:
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Sox10 probe33
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5A WT:
embryonic day 9.0
(more  )
Note: 15 somites
Specimen
5A WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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15 somites
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS14: migrating neural crest |
migratory neural crest cell |
Present |
Regionally restricted |
5A left
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Positive neural crest cells migrated out of the neural tube and into the pharyngeal region, but do not divide into separate arch populations.
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Specimen
5A -/-:
(close )
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Genetic Background:
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involves: 129X1/SvJ * BALB/c
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Mutant Allele(s):
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Foxi3tm1.2Akg/Foxi3tm1.2Akg
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Age:
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embryonic day 9.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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15 somites
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS14: migrating neural crest |
migratory neural crest cell |
Present |
Regionally restricted |
5A right
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Migration pattern was slightly altered in the mutants due to the absence of the otic placode and pharyngeal pouches, but there was no obvious difference in the numbers of cranial neural crest cells entering the pharyngeal region.
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Analysis Tools
