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Gene Expression Data
Assay Details
Assay
Reference: J:260151 Ito K, et al., Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters. Sci Rep. 2018 Jan 11;8(1):434
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427798
Gene symbol: Syp
Gene name: synaptophysin
Antibody: anti-synaptophysin (180130)
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 4A Fgf18+/+: embryonic day 18.5 (more )
Note: Double labeled: green - Syp and Prph (assay MGI:7427797); red - alpha-bungarotoxin.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 4A Fgf18+/+ Expression in axons.
Specimen 4A Fgf18-/-: embryonic day 18.5; Fgf18tm1Sjt/Fgf18tm1Sjt (more )
Note: Double labeled: green - Syp and Prph (assay MGI:7427797); red - alpha-bungarotoxin.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 4A Fgf18-/- Length and number of 2nd and 3rd axonal branches similar to those of wild type.
Specimen 4D Fgf18+/+: embryonic day 18.5 (more )
Note: Double labeled: green - Syp; red - alpha-bungarotoxin.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 4D Fgf18+/+ Expression in nerve terminals.
Specimen 4D Fgf18-/-: embryonic day 18.5; Fgf18tm1Sjt/Fgf18tm1Sjt (more )
Note: Double labeled: green - Syp; red - alpha-bungarotoxin.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 4D Fgf18-/- Expression at nerve terminal approximately one-third that seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory