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Gene Expression Data
Assay Details
Assay
Reference: J:199435 Barraud P, et al., Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427772
Gene symbol: Ncam1
Gene name: neural cell adhesion molecule 1
Antibody: anti-NCAM
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4A: embryonic day 16.5 (more )
Note: Coronal section. Double labeled: green - Ncam1; magenta - Omp (assay MGI:7427765).
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve neuron Present 4A
Specimen 4B: embryonic day 16.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Coronal section. Double labeled: green - Ncam1; magenta - Omp (assay MGI:7427765).
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve neuron Present 4B Olfactory nerve bundles are defasciculated in the homozygotes.
TS24: nasal cavity lamina propria neuron Present 4B Inappropriately migrating axons are seen within the lamina propria of the mutant.
Specimen 4I: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer neuron Present 4I Expression is seen in axons.
Specimen 4J: embryonic day 16.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer neuron Present 4J In the mutant, the ONL is much thinner in the dorsal and lateral regions of the bulb.
Specimen 4K: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer neuron Present 4K Expression is seen in axons.
Specimen 4L: embryonic day 16.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer neuron Present 4L1 , 4L In the mutant, the ventromedial ONL is thicker; instead of the bilateral staining seen in the wild type, the regions are merged due to an accumulation olfactory axons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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