About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7425000
Gene symbol: Hey2
Gene name: hairy/enhancer-of-split related with YRPW motif 2
Probe: Hey2 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7 - Hey2: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread 7c , 7b The ONL-OECs show expression.
TS24: olfactory nerve olfactory ensheathing cell Present 7b , 7d The mucosal OECs show expression.
TS24: trigeminal nerve Schwann cell Absent 7b , 7e The Schwann cells lack expression.
Specimen 9 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Present 9b , 9c The mucosal OECs show expression.
Specimen 9 - E13.5: embryonic day 13.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS22: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present 9d , 9e The ONL-OECs show expression.
TS22: olfactory nerve olfactory ensheathing cell Present 9f , 9d The mucosal OECs show expression.
Specimen 12k: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread 12k1 , 12k The ONL-OECs show expression.
Specimen 12l: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread 12l , 12l1 The ONL-OECs show expression. Expression levels in the mutant are much higher than those seen in wild type.
Specimen 12m: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present 12m1 , 12m The mucosal OECs show expression.
Specimen 12n: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present 12n1 , 12n The mucosal OECs show expression. Expression levels in the mutant are much higher than those seen in wild type.
Specimen S14E: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread S14E , S14E1 The ONL-OECs show expression.
Specimen S14F: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread S14F , S14F1 The ONL-OECs show expression. Expression levels in the mutant are comparable to those seen in wild type.
Specimen S14G: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present S14G1 , S14G The mucosal OECs show expression.
Specimen S14H: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present S14H1 , S14H The mucosal OECs show expression. Expression levels in the mutant are comparable to those seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory