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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7424891
Gene symbol: Npy
Gene name: neuropeptide Y
Probe: Npy cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1 - Npy: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform 1f , 1g The inner ONL-OECs show strong expression, the outer ONL-OECs much weaker expression.
TS24: olfactory nerve olfactory ensheathing cell Absent 1f , 1h The mucosal OECs lack expression.
TS24: trigeminal nerve Schwann cell Absent 1f , 1i The Schwann cells lack expression.
Specimen S10 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Absent S10B , S10C The mucosal OECs lack expression.
Specimen S10 - E13 - D1: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: main olfactory bulb layer olfactory ensheathing cell Present Widespread S10E1 , S10D1 The olfactory nerve layer OECs show expression.
Specimen S10 - E13 - D2: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: olfactory nerve olfactory ensheathing cell Absent S10D2 , S10E2 The mucosal OECs lack expression.
Specimen S13C: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S13C , S13C1 The inner ONL-OECs show strong expression, the outer ONL-OECs much weaker expression.
Specimen S13D: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S13D , S13D1 The inner ONL-OECs show strong expression, the outer ONL-OECs much weaker expression. Expression levels in the mutant are higher than those seen in wild type.
Specimen S14K: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S14K1 , S14K The inner ONL-OECs show strong expression, the outer ONL-OECs much weaker expression.
Specimen S14L: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S14L1 , S14L The inner ONL-OECs show strong expression, the outer ONL-OECs much weaker expression. Expression levels in the mutant are comparable to those seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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