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Gene Expression Data
Assay Details
Assay
Reference: J:242220 Ohlen SB, et al., BGP-15 prevents the death of neurons in a mouse model of familial dysautonomia. Proc Natl Acad Sci U S A. 2017 May 09;114(19):5035-5040
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7423801
Gene symbol: Mapk8
Gene name: mitogen-activated protein kinase 8
Antibody: anti-pJNK
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S3A Control +PBS: embryonic day 17.5; Elp1tm1c(KOMP)Wtsi/Elp1+, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant. Double labeled: green - JNK (Mapk8); red - Tuj-1 (Tubb3 assay MGI:7423803).
Structure Cell Type Level Pattern Image Note
TS25: dorsal root ganglion neuron Present S3A pJNK Control +PBS , S3A Composite Control +PBS
Specimen S3A Ikbkap-/- +PBS: embryonic day 17.5; Elp1tm1c(KOMP)Wtsi/Elp1tm1c(KOMP)Wtsi, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - JNK (Mapk8); red - Tuj-1 (Tubb3 assay MGI:7423803).
Structure Cell Type Level Pattern Image Note
TS25: dorsal root ganglion neuron Present S3A pJNK Ikbkap-/- +PBS , S3A Composite Ikbkap-/- +PBS Increased number of expressing cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory