About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:79481 Yu J, et al., Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development. 2002 Nov;129(22):5301-12
Assay type: RNA in situ
MGI Accession ID: MGI:7414046
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe112
Probe preparation: labelled with S35
Results
Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Strong Regionally restricted 1D Expression domain similar to that of Ptch.
TS22: ureteral mesenchyme Strong Regionally restricted 1D Expression domain similar to that of Ptch.

Specimen 1H: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: renal medulla Present Regionally restricted 1H inset , 1H Expression in mesenchyme of medulla and renal pelvis.
TS27: renal pelvis Present Regionally restricted 1H inset , 1H Expression in mesenchyme of medulla and renal pelvis.

Specimen 1L: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: ureter Present Regionally restricted 1L Expression restricted to thin layer of mesenchymal cells immediately adjacent to epithelium.
TS27: ureteral smooth muscle layer smooth muscle component ureter smooth muscle cell Absent 1L No expression in differentiated ureter smooth muscle cells.

Specimen 4E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4E inset , 4E Expression in mesenchymal cells surrounding collecting ducts.

Specimen 4F: embryonic day 14.5; Shhtm1Amc/Shhtm2Amc, Tg(Hoxb7-cre)13Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Absent 4F inset , 4F
TS22: maturing glomerular tuft Present 4F inset , 4F Expression in glomeruli not affected compared to wild type.

Specimen 4G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Regionally restricted 4G Expression in mesenchymal cells surrounding ureter.

Specimen 4H: embryonic day 14.5; Shhtm1Amc/Shhtm2Amc, Tg(Hoxb7-cre)13Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Absent 4H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/30/2025
MGI 6.24
The Jackson Laboratory