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Gene Expression Data
Assay Details
Assay
Reference: J:225740 Snowball J, et al., Endodermal Wnt signaling is required for tracheal cartilage formation. Dev Biol. 2015 Sep 1;405(1):56-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7407288
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Antibody: anti-Nkx2.1
Detection system: Secondary antibody
Results
Specimen 3E: embryonic day 14.5 (more )
Note: Triple labeled: blue - Nkx2-1; green - Sox9 (assay MGI:7407287); red - Acta2 (assay MGI:7388675).
Structure Level Pattern Image Note
TS22: trachea epithelium Present 3E
Specimen 3E': embryonic day 14.5 (more )
Note: Triple labeled: blue - Nkx2-1; green - Sox9 (assay MGI:7407287); red - Acta2 (assay MGI:7388675).
Structure Level Pattern Image Note
TS22: trachea epithelium Present 3E'
Specimen 3F: embryonic day 14.5; Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant. Triple labeled: blue - Nkx2-1; green - Sox9 (assay MGI:7407287); red - Acta2 (assay MGI:7388675).
Structure Level Pattern Image Note
TS22: trachea epithelium Present 3F
Specimen 3F': embryonic day 14.5; Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant. Triple labeled: blue - Nkx2-1; green - Sox9 (assay MGI:7407287); red - Acta2 (assay MGI:7388675).
Structure Level Pattern Image Note
TS22: trachea epithelium Present 3F'
Specimen 5B control: embryonic day 12.5 (more )
Note: Double labeled: blue - Nkx2-1; red - BrdU.
Structure Level Pattern Image Note
TS20: trachea epithelium Present 5B left
Specimen 5B cKO: embryonic day 12.5; Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant. Double labeled: blue - Nkx2-1; red - BrdU.
Structure Level Pattern Image Note
TS20: trachea epithelium Present 5B right Proliferation was decreased in mesenchyme, no change in the epithelium compared with the control (quantified in the 5C).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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