About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:260471 Gerhardt B, et al., Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27
Assay type: RNA in situ
MGI Accession ID: MGI:7388315
Gene symbol: Notum
Gene name: notum palmitoleoyl-protein carboxylesterase
Probe: Notum probe1
Probe preparation: Antisense RNA
Visualized with: Horseradish peroxidase
Results
Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trachea mesenchyme Present Regionally restricted 2A-1 Expressed in the ventral mesodermal region.
Specimen 2B control: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trachea mesenchyme Present Regionally restricted 2B-4 Expressed in the ventral mesodermal region.
Specimen 2B cKO: embryonic day 13.5; Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: trachea mesenchyme Weak 2B-9 Decreased expression compared with the control.
Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trachea mesenchyme Present Regionally restricted 3B Expressed in the ventral side.
Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Present Regionally restricted 3C Expressed in the subepithelial mesenchyme.
TS20: esophagus epithelium Present 3C
Specimen 3D control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trachea mesenchyme Present Regionally restricted 3D control Expressed in the ventral side.
Specimen 3D cKO: embryonic day 12.5; Shhtm1(EGFP/cre)Cjt/Shh+, Wlstm1.1Lan/Wlstm1.1Lan (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: trachea mesenchyme Weak 3D cKO Decreased expression compared with the control.
Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trachea mesenchyme Present Regionally restricted 3E Expressed in the periphery of mesenchymal condensations where cartilage develops.
Specimen S2 E12.5-1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Present Regionally restricted S2_4 Expressed in the subepithelial mesenchyme.
Specimen S2 E12.5-2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lobar bronchus mesenchyme Present Regionally restricted S2_7 Expressed in the subepithelial mesenchyme.
Specimen S2 E13.5-1: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Present Regionally restricted S2_5 Expressed in the subepithelial mesenchyme of the lung acini.
Specimen S2 E13.5-2: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Present Regionally restricted S2_8 Expressed in the subepithelial mesenchyme of the lung acini.
TS21: lobar bronchus mesenchyme Present Regionally restricted S2_8 Expressed in the subepithelial mesenchyme.
Specimen S2 E16.5-1: embryonic day 15.5-16.5 (more )
Structure Level Pattern Image Note
TS24: lung mesenchyme Present S2_3
Specimen S2 E16.5-2: embryonic day 15.5-16.5 (more )
Structure Level Pattern Image Note
TS24: lung mesenchyme Present Regionally restricted S2_6 Expressed in the subepithelial mesenchyme of the lung acini.
Specimen S3 jaw: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: jaw primordium mesenchyme Present Regionally restricted S3_left upper Expressed in the anterior mesenchyme.
Specimen S3 mesonefros: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mesonephric tubule Present Regionally restricted S3_right upper Expressed in anterior region of the mesonefros but excluded from the stroma.
Specimen S3 stomach: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: esophagus epithelium Present S3_left lower
TS20: stomach epithelium Present S3_left lower
TS20: stomach mesenchyme Absent S3_left lower
Specimen S3 spine: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: axial skeleton Present Regionally restricted S3_right lower Expressed in a periodical segmented pattern in the periphery of the vertebral bodies.
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory