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Gene Expression Data
Assay Details
Assay
Reference: J:228859 Fu J, et al., Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration. PLoS Genet. 2014 Oct;10(10):e1004579
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7387120
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated caspase3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2A P4 control: postnatal day 4; Senp2tm2.1Whsu/Senp2+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. The genotype for control mice could either be Nestin-Cre; SENP2SUMOFx/+ or SENP2SUMOFx/Fx.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2A P4 control
Specimen 2A P4 cKO: postnatal day 4; Senp2tm2.1Whsu/Senp2tm2.1Whsu, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2A P4 cKO Increased expression (1.52+/-0.33%) compared with the control (0.46+/-0.12%).
Specimen 2A P7 control: postnatal day 7; Senp2tm2.1Whsu/Senp2+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. The genotype for control mice could either be Nestin-Cre; SENP2SUMOFx/+ or SENP2SUMOFx/Fx.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2A P7 control
Specimen 2A P7 cKO: postnatal day 7; Senp2tm2.1Whsu/Senp2tm2.1Whsu, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2A P7 cKO Highly increased expression (9.4+/-0.59%) compared with the control (0.82+/-0.08%).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory