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Gene Expression Data
Assay Details
Assay
Reference: J:314181 Holzman MA, et al., HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384941
Gene symbol: Pparg
Gene name: peroxisome proliferator activated receptor gamma
Antibody: anti-PPAR gamma (MA5-14889)
Detection system: Secondary antibody
Results
Specimen 1I/J: postnatal month 3; Tg(Hoxa5-cre)447BLjea/0 (more )
Note: Double labeled: red - Pparg; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS28: brown fat brown adipocyte Present Regionally restricted 1J , 1I Nuclear expression in adipocytes.
Specimen 5A: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: brown fat brown adipocyte Present 5A
Specimen 5B: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: brown fat brown adipocyte Present 5B
Specimen 5F: embryonic day 18.5; Hoxa5tm1Rob/Hoxa5tm1Rob (more )
Structure Cell Type Level Pattern Image Note
TS26: brown fat brown adipocyte Present Regionally restricted 5F Adipocyte density appeared reduced compared to controls.
Specimen 5G: embryonic day 18.5; Hoxa5tm1Rob/Hoxa5tm1Rob (more )
Structure Cell Type Level Pattern Image Note
TS26: brown fat brown adipocyte Present Regionally restricted 5G Adipocyte density appeared reduced compared to controls.
Specimen S3A/B/C: postnatal day 2; Hoxa5tm1.1Ljea/Hoxa5+, Meox1tm1(cre)Jpa/Meox1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: brown fat brown adipocyte Present S3A , S3B , S3C
Specimen S3E/F/G: postnatal day 2; Hoxa5tm1.1Ljea/Hoxa5tm1.1Ljea, Meox1tm1(cre)Jpa/Meox1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: brown fat brown adipocyte Present Regionally restricted S3G , S3E , S3F Smaller BAT area and reduced adipocyte density compared to control.
Specimen 8A: embryonic day 14.5; Hoxa5tm1Rob/Hoxa5+ (more )
Note: Double labeled: green - Pparg; red - Myh4 (assay MGI:7384937).
Structure Cell Type Level Pattern Image Note
TS22: brown fat brown adipocyte Present 8A
Specimen 8B: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: brown fat brown adipocyte Present Regionally restricted 8B Smaller BAT area and reduced adipocyte density compared to control.
Specimen 8C: embryonic day 14.5; Hoxa5tm1Rob/Hoxa5tm1Rob (more )
Note: Double labeled: green - Pparg; red - Myh4 (assay MGI:7384937).
Structure Cell Type Level Pattern Image Note
TS22: brown fat brown adipocyte Present 8C
Specimen 8D: embryonic day 14.5; Hoxa5tm1Rob/Hoxa5tm1Rob (more )
Structure Cell Type Level Pattern Image Note
TS22: brown fat brown adipocyte Present Regionally restricted 8D Smaller BAT area and reduced adipocyte density compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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08/05/2025
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