Meox1^tm1(cre)Jpa
Targeted Allele Detail

Summary

• Symbol: Meox1^tm1(cre)Jpa
• Name: mesenchyme homeobox 1; targeted mutation 1, Juha Partanen
• MGI ID: MGI:3611205
• Synonyms: Meox1^Cre21, Mox1cre
• Gene: Meox1 Location: Chr11:101768336-101785200 bp, - strand Genetic Position: Chr11, Syntenic
• Alliance: Meox1^tm1(cre)Jpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102739
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Meox1^tm1(cre)Jpa expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Meox1 (MGI:103220)

• Mutation details: A cassette containing a splice acceptor, an IRES-EGFP-cre, the pA sequence, and a kanamycin/neomycin resistance gene was inserted into the locus. Cre expression was expected in the presomatic and somatic mesoderm. EGFP activity was not detected in mutant embryos between E9.5-11.5, possibly due to a low level of expression of the EGFP0cre fusion protein mediated by the IRES sequence. (J:102739)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Meox1 (mouse) Summary of all recombinase alleles driven by Meox1. Comparative matrix view of recombinase activities Alliance mouse Meox1 gene page

Expression

In Mice Carrying this Mutation:

60 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meox1 Mutation: 17 strains or lines available

Notes

Lines Meox1^Cre21 and Meox1^Cre37 were created.

References

• Original: J:102739 Jukkola T, et al., Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm. Genesis. 2005 Nov;43(3):148-53
• All: 7 reference(s)