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Gene Expression Data
Assay Details
Assay
Reference: J:219045 Dai X, et al., Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 2013;11:107
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384426
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Results
Specimen 5A,A': embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Ilktm1Star/Ilk+ (more )
Note: Conditional mutant. Double labeled: green - Acta2; red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS20: arch of aorta Present 5A , 5A'
TS20: outflow tract blood vessel smooth muscle cell Present Regionally restricted 5A' , 5A Authors report well-formed smooth muscle layers.
Specimen 5B,B': embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Ilktm1Star/Ilktm1Star (more )
Note: Conditional mutant. Double labeled: green - Acta2; red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS20: arch of aorta Trace Regionally restricted 5B' , 5B Expression greatly reduced in cells derived from neural crest cells.
TS20: outflow tract blood vessel smooth muscle cell Trace Patchy 5B' , 5B Expression greatly reduced in cells derived from neural crest cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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