Foxa2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7380666
Gene symbol:	Foxa2
Gene name:	forkhead box A2

Antibody:	4C7
Detection system:	Secondary antibody

Results

Specimen 1A FoxA2 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		1A FoxA2 WT

Specimen 1A FoxA2 bromi: embryonic day 10.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		1A FoxA2 bromi

Specimen 2 FoxA2 WT: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube floor plate	Present		2_FoxA2 WT

Specimen 2 FoxA2 bromi: embryonic day 9.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube	Absent		2_FoxA2 bromi

Specimen 2 FoxA2 Ptch1: embryonic day 9.5; Ptch1^tm1Mps/Ptch1^tm1Mps (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Widespread	2_FoxA2 Ptch1	Broadly expressed throughout open neural tube.

Specimen 2 FoxA2 bromi,Ptch1: embryonic day 9.5; Ptch1^tm1Mps/Ptch1^tm1Mps, Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube	Absent		2_FoxA2 bromi,Ptch1

Specimen 3A FoxA2 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		3A FoxA2 WT

Specimen 3A FoxA2 bromi: embryonic day 10.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		3A FoxA2 bromi

Specimen 3A FoxA2 Gli3xt: embryonic day 10.5; Gli3^Xt-J/Gli3^Xt-J (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		3A FoxA2 Gli3xt	Authors report normal expression.

Specimen 3A FoxA2 bromi,Gli3xt: embryonic day 10.5; Gli3^Xt-J/Gli3^Xt-J, Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	3A FoxA2 bromi,Gli3xt	Authors report disruption of floor plate specification.

Specimen 3B FoxA2 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		3B FoxA2 WT

Specimen 3B FoxA2 bromi: embryonic day 10.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		3B FoxA2 bromi

Specimen 3B FoxA2 Gli2: embryonic day 10.5; Gli2^tm1Alj/Gli2^tm1Alj (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		3B FoxA2 Gli2

Specimen 3B FoxA2 bromi,Gli2: embryonic day 10.5; Gli2^tm1Alj/Gli2^tm1Alj, Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		3B FoxA2 bromi,Gli2

Specimen S2C FoxA2 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	S2C FoxA2 WT

Specimen S2C FoxA2 bromi: embryonic day 10.5; Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		S2C FoxA2 bromi

Specimen S2C FoxA2 Rab23opb2: embryonic day 10.5; Rab23^opb2/Rab23^opb2 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present	Regionally restricted	S2C FoxA2 Rab23opb2	Expression domain shifted compared to wild type.

Specimen S2C FoxA2 bromi,Rab23opb2: embryonic day 10.5; Rab23^opb2/Rab23^opb2, Tbc1d32^bromi/Tbc1d32^bromi (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		S2C FoxA2 bromi,Rab23opb2	Authors report same dorsalized phenotype as in bromi single mutants.

Specimen S4B FoxA2 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		S4B FoxA2 WT

Specimen S4B FoxA2 RRF/RRF: embryonic day 10.5; Tbc1d32^{Gt(RRF165)Byg}/Tbc1d32^{Gt(RRF165)Byg} (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Absent		S4B FoxA2 RRF/RRF	Expression identical to that of bromi mutants.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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