About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:329930 Guertin TM, et al., Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse. Dev Biol. 2022 Nov;491:31-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378255
Gene symbol: Gata4
Gene name: GATA binding protein 4
Antibody: anti-GATA-4 (sc-9053)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A': embryonic day 10.5 (more )
Note: Control was either Rdh10+/+ or Rdh10trex/+. Triple labeled: green - Gata4; red - Hnf4a (assay MGI:7378252); white - Isl1 (assay MGI:7378256).
Structure Level Pattern Image Note
TS17: hepatic primordium Present Regionally restricted 5A' HNF4a-positive hepatoblasts are distributed throughout the GATA4-positive hepatic mesoderm of both the rostral lobe (blue asterisk) and the smaller caudal lobes (yellow asterisks).
TS17: septum transversum Present Regionally restricted 5A' The rostral lobe was bounded by the loosely organized Gata4-positive septum transversum mesenchyme.
Specimen 5B': embryonic day 10.5; Rdh10trex/Rdh10trex (more )
Note: Triple labeled: green - Gata4; red - Hnf4a (assay MGI:7378252); white - Isl1 (assay MGI:7378256).
Structure Level Pattern Image Note
TS17: septum transversum Present Regionally restricted 5B' The rostral liver lobe was bounded by a loosely organized Gata4-positive septum transversum mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory