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Gene Expression Data
Assay Details
Assay
Reference: J:329930 Guertin TM, et al., Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse. Dev Biol. 2022 Nov;491:31-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378254
Gene symbol: Hnf4a
Gene name: hepatic nuclear factor 4, alpha
Antibody: Anti-HNF-4 alpha (C-19, sc-6556)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4I Anterior: embryonic day 9.5 (more )
Note: Anterior liver bud section. 26-27 somites. Control was either Rdh10+/+ or Rdh10trex/+.
Structure Cell Type Level Pattern Image Note
TS15: hepatic primordium hepatoblast Present 4I

Specimen 4J Middle: embryonic day 9.5 (more )
Note: Middle liver bud section. 26-27 somites. Control was either Rdh10+/+ or Rdh10trex/+.
Structure Cell Type Level Pattern Image Note
TS15: hepatic primordium hepatoblast Present 4J

Specimen 4K Anterior: embryonic day 9.5; Rdh10trex/Rdh10trex (more )
Note: Anterior liver bud section. 23-24 somites.
Structure Cell Type Level Pattern Image Note
TS15: hepatic primordium hepatoblast Present 4K

Specimen 4L Middle: embryonic day 9.5; Rdh10trex/Rdh10trex (more )
Note: Middle liver bud section. 23-24 somites.
Structure Cell Type Level Pattern Image Note
TS15: hepatic primordium hepatoblast Present 4L

Specimen S2 left: embryonic day 10.5 (more )
Note: Control was either Rdh10+/+ or Rdh10trex/+.
Structure Cell Type Level Pattern Image Note
TS17: hepatic primordium hepatoblast Present S2_left

Specimen S2 right: embryonic day 10.5; Rdh10trex/Rdh10trex (more )
Structure Cell Type Level Pattern Image Note
TS17: hepatic primordium hepatoblast Present Single cells S2_right Embryos with severe phenotype contain few to no immunopositive heptaoblasts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory