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Gene Expression Data
Assay Details
Assay
Reference: J:329930 Guertin TM, et al., Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse. Dev Biol. 2022 Nov;491:31-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378253
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1 (#11-002)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3C Anterior: embryonic day 9.5 (more )
Note: Anterior liver bud section. Control was either Rdh10+/+ or Rdh10trex/+. 27 somites. Double labeled: green - Prox1; red - Hnf4a (assay MGI:7378252).
Structure Level Pattern Image Note
TS15: hepatic primordium Present Uniform 3C Anterior Merge , 3C Anterior Prox1

Specimen 3C Middle: embryonic day 9.5 (more )
Note: Middle liver bud section. Control was either Rdh10+/+ or Rdh10trex/+. 27 somites. Double labeled: green - Prox1; red - Hnf4a (assay MGI:7378252).
Structure Level Pattern Image Note
TS15: hepatic primordium Present Uniform 3C Middle Prox1 , 3C Middle Merge

Specimen 3D Anterior: embryonic day 9.5; Rdh10trex/Rdh10trex (more )
Note: Anterior liver bud section. 23-24 somites. Double labeled: green - Prox1; red - Hnf4a (assay MGI:7378252).
Structure Level Pattern Image Note
TS15: hepatic primordium Present Uniform 3D Anterior Merge , 3D Anterior Prox1 Uniform expression was detected in the mutant anterior liver bud, as in the control.

Specimen 3D Middle: embryonic day 9.5; Rdh10trex/Rdh10trex (more )
Note: Middle liver bud section. 23-24 somites. Double labeled: green - Prox1; red - Hnf4a (assay MGI:7378252).
Structure Level Pattern Image Note
TS15: hepatic primordium Present Uniform 3D Middle Merge , 3D Middle Prox1 Uniform expression was detected in the mutant middle liver bud, as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory