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Gene Expression Data
Assay Details
Assay
Reference: J:323190 Guo T, et al., KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. Elife. 2022 Feb 25;11:e74595
Assay type: RNA in situ
MGI Accession ID: MGI:7366972
Gene symbol: Trp53
Gene name: transformation related protein 53
Probe: Mm-Trp53 (402331)
Probe preparation: Antisense
Visualized with: Chromogenic
Results
Specimen 3D,E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 3E , 3D
Specimen 3F,G: embryonic day 13.5; Kdm6btm1.1Rbo/Kdm6btm1.1Rbo, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf Weak 3F , 3G Significantly decreased expression in palatal region.
Specimen 8B,E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 8E , 8B
Specimen 8C,F: embryonic day 13.5; Kdm6btm1.1Rbo/Kdm6btm1.1Rbo, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Weak 8F , 8C
Specimen 8D,G: embryonic day 13.5; Ezh2tm2Sho/Ezh2+, H2az2Tg(Wnt1-cre)11Rth/H2az2+, Kdm6btm1.1Rbo/Kdm6btm1.1Rbo (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 8G , 8D Expression restored in cranial neural crest (CNC)-derived palatal msenchyme
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory