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Gene Expression Data
Assay Details
Assay
Reference: J:323190 Guo T, et al., KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. Elife. 2022 Feb 25;11:e74595
Assay type: RT-PCR
MGI Accession ID: MGI:7366966
Gene symbol: Trp53
Gene name: transformation related protein 53
Probe: Trp53-pQ, Trp53-pR
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh.
Results
Image: 8H ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Control E13.5 TS21: palatal shelf mesenchyme Present Not Specified; total RNA Not Specified Not Specified
Wnt1Cre;Kdm6bfl/fl E13.5 TS21: palatal shelf mesenchyme Weak (a) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6J * CBA/J Kdm6btm1.1Rbo/Kdm6btm1.1Rbo, H2az2Tg(Wnt1-cre)11Rth/H2az2+Not Specified Conditional mutant.
Wnt1Cre;Kdm6bfl/fl;Ezh2fl/+ E13.5 TS21: palatal shelf mesenchyme Present (b) Not Specified; total RNA involves: 129S1/Sv * 129S4/SvJae * C57BL/6J * CBA/J Ezh2tm2Sho/Ezh2+, H2az2Tg(Wnt1-cre)11Rth/H2az2+, Kdm6btm1.1Rbo/Kdm6btm1.1RboNot Specified Conditional mutant.
Notes:
(a) Decreased expression in cranial neural crest (CNC)-derived palatal mesenchyme.
(b) Expression in palatal mesenchyme restored.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory