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Gene Expression Data
Assay Details
Assay
Reference: J:329558 Liu W, et al., Expression of Calbindin-D28K in the Developing and Adult Mouse Cochlea. J Histochem Cytochem. 2022 Aug;70(8):583-596
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7356366
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody
Results
Specimen 1B: embryonic day 16.5 (more )
Note: In apical turn of cochlea. Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Level Pattern Image Note
TS24: greater epithelial ridge Present Regionally restricted 1B Expression in portion of greater epithelial ridge. No co-expression with Calb1.
Specimen 1C: embryonic day 16.5 (more )
Note: In middle turn of cochlea. Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Level Pattern Image Note
TS24: greater epithelial ridge Present Regionally restricted 1C Expression localized in most external part of greater epithelial ridge. No co-expression with Calb1.
Specimen 1D: embryonic day 16.5 (more )
Note: In middle turn of cochlea. Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Cell Type Level Pattern Image Note
TS24: organ of Corti cochlear inner hair cell Present Regionally restricted 1D Expression in hair cell and supporting cell nuclei.
TS24: organ of Corti cochlear outer hair cell Present Regionally restricted 1D Expression in hair cell and supporting cell nuclei.
TS24: organ of Corti Deiter's cell Present Regionally restricted 1D Expression in hair cell and supporting cell nuclei.
Specimen 1E: embryonic day 16.5 (more )
Note: Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 1E Expression in glial cells of Rosenthal's canal.
Specimen 1F: embryonic day 18.5 (more )
Note: In apical turn of cochlea. Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti cochlear inner hair cell Absent 1F In apical turn of cochlea, inner hair cells remain unlabelled.
Specimen 1G: embryonic day 18.5 (more )
Note: In middle turn of cochlea. Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Cell Type Level Pattern Image Note
TS26: greater epithelial ridge Present 1G
TS26: organ of Corti cochlear inner hair cell Present 1G In middle turn of cochlea, expression in inner hair cells.
TS26: organ of Corti interdental cell of cochlea Present 1G
Specimen 1I: embryonic day 18.5 (more )
Note: In basal turn of cochlea. Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Cell Type Level Pattern Image Note
TS26: cochlea Deiter's cell Present 1I
Specimen 2B: postnatal day 1 (more )
Note: Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Level Pattern Image Note
TS27: greater epithelial ridge Present Regionally restricted 2B Expression domain extends medially into medial portion of greater epithelial ridge.
Specimen 3B: postnatal day 5 (more )
Note: Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Level Pattern Image Note
TS28: greater epithelial ridge Present Regionally restricted 3B Expression domain extends medially into medial portion of greater epithelial ridge.
Specimen 3H: postnatal day 8 (more )
Note: Double labeled: red - Sox2; green - Calb1 (assay MGI:7356365).
Structure Level Pattern Image Note
TS28: greater epithelial ridge Present Regionally restricted 3H Expression domain extends medially into medial portion of greater epithelial ridge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory