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Gene Expression Data
Assay Details
Assay
Reference: J:328554 Wei X, et al., Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis. Cell Rep. 2022 Sep 6;40(10):111313
Assay type: RNA in situ
MGI Accession ID: MGI:7341603
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Probe: Mm-Lgr5 probe2
Probe preparation: Antisense
Visualized with: Chromogenic
Results
Specimen 2A E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epithelium of urogenital sinus Present 2A E15.5 (lower) , 2A E15.5 (upper) Highly expressed in urogenital sinus epithelia and mesenchyme.
TS23: mesenchyme of urogenital sinus Present 2A E15.5 (lower) , 2A E15.5 (upper) Highly expressed in urogenital sinus epithelia and mesenchyme.
Specimen 2A E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epithelium of urogenital sinus Present 2A E18.5 (upper) , 2A E18.5 (lower) Expression in epithelium remained comparable to that at E15.5.
TS26: mesenchyme of urogenital sinus Strong 2A E18.5 (upper) , 2A E18.5 (lower) Expression in mesenchyme upregulated.
Specimen 2A Week 2: postnatal week 2 (more )
Structure Cell Type Level Pattern Image Note
TS28: prostate duct prostate stromal cell Present Regionally restricted 2A Week 2 Expression in stromal cells confined at proximal prostatic ducts.
Specimen 2A Week 2 Proximal Duct: postnatal week 2 (more )
Structure Cell Type Level Pattern Image Note
TS28: prostate duct prostate stromal cell Present Regionally restricted 2A Week 2 Proximal Duct Expression in stromal cells confined at proximal prostatic ducts.
Specimen 2A Week 2 Distal Duct: postnatal week 2 (more )
Structure Cell Type Level Pattern Image Note
TS28: prostate duct epithelial cell of prostatic duct Weak Regionally restricted 2A Week 2 Distal Duct Expression still present at low level in epithelial cells at distal prostatic ducts.
Specimen 2A Week 10: postnatal week 10 (more )
Structure Cell Type Level Pattern Image Note
TS28: prostate duct prostate stromal cell Present Regionally restricted 2A Week 10 Expression in stromal cells confined at proximal prostatic ducts.
Specimen 2A Week 10 Proximal Duct: postnatal week 10 (more )
Structure Cell Type Level Pattern Image Note
TS28: prostate duct prostate stromal cell Present Regionally restricted 2A Week 10 Proximal Duct Expression in stromal cells confined at proximal prostatic ducts.
Specimen 2A Week 10 Distal Duct: postnatal week 10 (more )
Structure Cell Type Level Pattern Image Note
TS28: prostate duct epithelial cell of prostatic duct Trace Regionally restricted 2A Week 10 Distal Duct Expression almost undetectable in distal prostatic epithelial cells at week 10.
Specimen S2A Small Intestine: postnatal week 10 (more )
Structure Level Pattern Image Note
TS28: small intestine Present Regionally restricted S2A Small Intestine Expression in stromal cells.
Specimen S2A Colon: postnatal week 10 (more )
Structure Level Pattern Image Note
TS28: colon Present Regionally restricted S2A Colon Expression in stromal cells.
Specimen S2A Stomach: postnatal week 10 (more )
Structure Level Pattern Image Note
TS28: stomach Present Regionally restricted S2A Stomach Expression in stromal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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