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Gene Expression Data
Assay Details
Assay
Reference: J:327815 Beauchamp MC, et al., Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion. Int J Mol Sci. 2022 Aug 12;23(16)
Assay type: RT-PCR
MGI Accession ID: MGI:7341561
Gene symbol: Mdm2
Gene name: transformed mouse 3T3 cell double minute 2
Results
Image: 6B ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified (b) Amount Genetic BackgroundMutant Allele(s)Sex Note
ctl E9.5 TS15: head Present Weak Not Specified involves: 129P2/OlaHsd * C57BL/6 * CD-1 Eftud2em1Lajm/Eftud2em2Lajm, Trp53tm1Brn/Trp53+Not Specified
Eftud2ncc-/-;Trp53ncc+/+ E9.5 TS15: head Present Weak Not Specified involves: 129P2/OlaHsd * C3H * C57BL/6 * CD-1 E2f1Tg(Wnt1-cre)2Sor/E2f1+, Eftud2em1Lajm/Eftud2em2LajmNot Specified Conditional mutant.
Eftud2ncc-/-;Trp53ncc+/- E9.5 TS15: head Present Present (c) Not Specified involves: 129P2/OlaHsd * C3H * C57BL/6 * CD-1 E2f1Tg(Wnt1-cre)2Sor/E2f1+, Eftud2em1Lajm/Eftud2em2Lajm, Trp53tm1Brn/Trp53+Not Specified Conditional mutant.
Eftud2ncc-/-;Trp53ncc-/- E9.5 TS15: head Present Present (c) Not Specified involves: 129P2/OlaHsd * C3H * C57BL/6 * CD-1 E2f1Tg(Wnt1-cre)2Sor/E2f1+, Eftud2em1Lajm/Eftud2em2Lajm, Trp53tm1Brn/Trp53tm1BrnNot Specified Conditional mutant.
Notes:
(a) FL
(b) without exon 3
(c) Significantly increased expression of mis-spliced transcript missing exon 3 compared to controls or Eftud2ncc-/-.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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