Eftud2^em1Lajm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Eftud2^em1Lajm
• Name: elongation factor Tu GTP binding domain containing 2; endonuclease-mediated mutation 1, Loydie Anne Jerome-Majewska
• MGI ID: MGI:6358537
• Gene: Eftud2 Location: Chr11:102729299-102771811 bp, - strand Genetic Position: Chr11, 66.48 cM
• Alliance: Eftud2^em1Lajm page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 2. (J:278323)

Disease models

Expression

In Mice Carrying this Mutation:

81 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eftud2 Mutation: 58 strains or lines available

References

• Original: J:278323 Beauchamp MC, et al., Loss of function mutation of Eftud2, the gene responsible for mandibulofacial dysostosis with microcephaly (MFDM), leads to pre-implantation arrest in mouse. PLoS One. 2019;14(7):e0219280
• All: 2 reference(s)