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Gene Expression Data
Assay Details
Assay
Reference: J:273083 Joseph DB, et al., Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds. Dev Biol. 2019 Mar 15;447(2):157-169
Assay type: RNA in situ
MGI Accession ID: MGI:7339291
Gene symbol: Nkx3-1
Gene name: NK3 homeobox 1
Probe: Nkx3-1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 18.5; Dnmt1tm2Jae/Dnmt1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: prostate bud Present 1A Similar as in the cre negative mice (quantified in S2B).
Specimen 1B: embryonic day 18.5; Dnmt1tm2Jae/Dnmt1tm2Jae, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: prostate bud Present 1B Fewer total prostatic buds and specifically fewer dorsal and anterior prostatic buds than controls (quantified in S2A).
Specimen 1D: embryonic day 18.5; Dnmt1tm2Jae/Dnmt1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: prostate epithelium epithelial cell of prostate Present 1D
Specimen 1E: embryonic day 18.5; Dnmt1tm2Jae/Dnmt1tm2Jae, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: prostate epithelium epithelial cell of prostate Present 1E Prostatic buds were unusually short and wide compared to control buds.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory