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Gene Expression Data
Assay Details
Assay
Reference: J:219823 Rosin JM, et al., Mice lacking the transcription factor SHOX2 display impaired cerebellar development and deficits in motor coordination. Dev Biol. 2015 Mar 1;399(1):54-67
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7336397
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody
Results
Specimen 5D: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: cerebellum external granule cell layer cerebellar granule cell Present 5D' , 5D" , 5D Expressed in granule cell precursors and granule cells.
TS27: cerebellum internal granule cell layer Absent 5D' , 5D" , 5D
Specimen 5E: postnatal day 1; Shox2tm1Ddu/Shox2tm1.1Ddu, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: cerebellum external granule cell layer cerebellar granule cell Present 5E , 5E' , 5E" Expressed in granule cell precursors and granule cells. A reduction in the thickness or number of granule cell precursors was seen.
TS27: cerebellum internal granule cell layer cerebellar granule cell Present 5E" , 5E' , 5E Expressed in granule cell precursors and granule cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory