About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:219823 Rosin JM, et al., Mice lacking the transcription factor SHOX2 display impaired cerebellar development and deficits in motor coordination. Dev Biol. 2015 Mar 1;399(1):54-67
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7336390
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase 3
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 3G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum Ambiguous 3G

Specimen 3H: postnatal day 0; Shox2tm1Ddu/Shox2tm1.1Ddu, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cerebellum Ambiguous 3H Similar as in the control.

Specimen 3I: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: inferior colliculus Present Single cells 3I
TS27: superior colliculus Present Single cells 3I

Specimen 3J: postnatal day 0; Shox2tm1Ddu/Shox2tm1.1Ddu, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: inferior colliculus Present 3J Increase in the number of positive cells compared with the control.
TS27: superior colliculus Present 3J Increase in the number of positive cells compared with the control.

Specimen S3E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Ambiguous S3E

Specimen S3F: embryonic day 11.5; Shox2tm1Ddu/Shox2tm1.1Ddu, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: cerebellum primordium Ambiguous S3F Similar as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/30/2025
MGI 6.24
The Jackson Laboratory