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Gene Expression Data
Assay Details
Assay
Reference: J:203995 Lee S, et al., Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7333005
Gene symbol: Krt14
Gene name: keratin 14
Antibody: Anti-K14
Results
Specimen 2A control: embryonic day 18.5 (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 2A left
Specimen 2A -/-: embryonic day 18.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS26: epidermis keratinocyte Present Widespread 2A right Expressed throughout the epidermis in contrast to their restricted expression to basal keratinocytes in controls.
TS26: epidermis basal layer keratinocyte Present 2A right
Specimen 3F control: embryonic day 18.5 (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 3F left
Specimen 3F shd+/-; Er+/-: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 3F right
TS26: epidermis keratinocyte Present 3F right The epidermis was greatly thickened and the cornified layer displayed gaps, with positive keratinocytes spilling out onto the surface.
Specimen 4B control: embryonic day 14.5 (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS22: epidermis basal layer keratinocyte Present 4B left
TS22: epidermis intermediate layer keratinocyte Ambiguous 4B left Largely negative.
Specimen 4B -/-: embryonic day 14.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS22: epidermis keratinocyte Present 4B right Dorsal epidermis was greatly thickened and stained positive.
TS22: epidermis basal layer keratinocyte Present 4B right
Specimen 4H control: embryonic day 18.5 (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 4H left
Specimen 4H shd-/-; p63+/-: embryonic day 18.5; Kdf1shd/Kdf1shd, Trp63tm2Brd/Trp63+ (more )
Note: Double labeled: red - Krt14; green - Itgb4 (assay MGI:7333006).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 4H right Normal thickness and expression was restored in lateral (barrier-restored) regions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory