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Gene Expression Data
Assay Details
Assay
Reference: J:185804 Larkins CE, et al., Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia. Dev Biol. 2012 Jul 1;367(1):15-24
Assay type: RNA in situ
MGI Accession ID: MGI:7331346
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 cDNA10
Probe preparation: Antisense RNA
Results
Specimen 3A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 3A Expressed in the left side (90%).
Specimen 3B: embryonic day 8.5; Arl13bhnn/Arl13bhnn (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present 3B Bilateral expression (>30%).
Specimen 3C: embryonic day 8.5; Arl13bhnn/Arl13bhnn, Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Absent 3C 6 out of 6 mutant embryos.
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Absent 10% embryos with no expression (summarized in 3D).
Specimen not shown: embryonic day 8.5; Arl13bhnn/Arl13bhnn (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Absent ~30% embryos with no expression (summarized in 3D).
Specimen not shown: embryonic day 8.5; Arl13bhnn/Arl13bhnn (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted ~30% embryos expressed on the left; 5% on the right (summarized in 3D).
Specimen not shown: embryonic day 9.5; Arl13bhnn/Arl13bhnn (more )
Structure Level Pattern Image Note
TS15: mesenchyme derived from splanchnopleure Present Most often expressed bilaterally or exclusively on the left side.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory